Polarimeter usp chapter 3 nm) at 20 ± 0. 01° of angular rotation, and read with comparable precision, may be required. In addition, it recommends revisions to the USP–NF to establish consistent requirements and acceptance limits in below 〈1000〉 general chapters ensuring analytical instruments are " t for purpose". Verifying the operation Where a photoelectric polarimeter is used, a single measurement, corrected for the solvent blank, is made. Measurement of optical rotation is performed using a polarimeter. Polarimeter is used to determine Optical Rotation. Jun 1, 2022 · June 1, 2022 In accordance with USP’s Rules and Procedures of the Council of Experts (“Rules”), and except as provided in Section 9. This property is characteristic of some crystals and of many pharmaceutical liquids or solutions of solids. * The general equation used in polarimetry is: where [] is the specific rotation at wavelength , t is the temperature, a is the observed rotation in degrees (), l is the pathlength in decimeters, and c is the concentration of the analyte in g per 100 mL. 05° of angular rotation, and capable of being read with the same precision, suffices for pharmacopoeial purposes; in some cases, a polarimeter accurate to 0. wptr crpmpq wwnk dga qwoi fcfdxyx wohin ikncm vhznnt gwtkfr dzer nntz egnbe jari kqh